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In Vitro Assembly and Stabilization of Dengue and Zika Virus Envelope Protein Homo-Dimers

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Abstract Zika virus (ZIKV) and the 4 dengue virus (DENV) serotypes are mosquito-borne Flaviviruses that are associated with severe neuronal and hemorrhagic syndromes. The mature flavivirus infectious virion has 90 envelope (E) protein homo-dimers that pack tightly to form a smooth protein coat with icosahedral symmetry. Human antibodies that strongly neutralize ZIKV and DENVs recogniz... https://www.uvmebrl.com/product-category/subscription/
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